long-chain fatty acid-CoA ligase activity [GO_0004467]

Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

Tags:

Class
GO

long-chain fatty acid-CoA ligase activity

ID: GO_0004467

Class

Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.

While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

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Classification

fatty acid-CoA ligase activity

Relationships

is part of: long-chain fatty acid metabolic process

Alternative Names

Synonym	Scope	Reference
lignoceroyl-CoA synthase activity	related synonym
acyl-CoA ligase activity	related synonym
fatty acid thiokinase (long-chain) activity	related synonym
long-chain fatty acyl coenzyme A synthetase activity	related synonym
long chain fatty acyl-CoA synthetase activity	related synonym
long-chain acyl CoA synthetase activity	related synonym
LCFA synthetase activity	related synonym
long-chain fatty acid activation	related synonym
long-chain acyl-coenzyme A synthetase activity	related synonym
acyl-CoA synthetase activity	related synonym	6.2.1.3
stearoyl-CoA synthetase	narrow synonym
pristanoyl-CoA synthetase	narrow synonym
acyl-activating enzyme activity	broad synonym
long-chain acyl-CoA synthetase activity	exact synonym
long-chain-fatty-acid-CoA ligase activity	exact synonym
long-chain-fatty-acyl-CoA synthetase activity	exact synonym
thiokinase	related synonym

References

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}, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_broad_synonym", "label": "acyl-activating enzyme activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_related_synonym", "label": "long-chain fatty acyl coenzyme A synthetase activity", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_related_synonym", "label": "thiokinase", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } }, { "synonym": { "scope": "has_narrow_synonym", "label": "pristanoyl-CoA synthetase", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } } ], "def_pubs": [] }

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